Detalhe da pesquisa
1.
Small-molecule-induced epigenetic rejuvenation promotes SREBP condensation and overcomes barriers to CNS myelin regeneration.
Cell
; 187(10): 2465-2484.e22, 2024 May 09.
Artigo
Inglês
| MEDLINE | ID: mdl-38701782
2.
Differentiated embryonic chondrocyte expressed gene-1 is a central signaling component in the development of collagen-induced rheumatoid arthritis.
J Biol Chem
; 299(3): 102982, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36739947
3.
The COVID-19 Oral Drug Molnupiravir Is a CES2 Substrate: Potential Drug-Drug Interactions and Impact of CES2 Genetic Polymorphism In Vitro.
Drug Metab Dispos
; 50(9): 1151-1160, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35790245
4.
MicroRNA-30c-1-3p is a silencer of the pregnane X receptor by targeting the 3'-untranslated region and alters the expression of its target gene cytochrome P450 3A4.
Biochim Biophys Acta
; 1859(9): 1238-1244, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27085140
5.
Circadian rhythmicity: A functional connection between differentiated embryonic chondrocyte-1 (DEC1) and small heterodimer partner (SHP).
Arch Biochem Biophys
; 631: 11-18, 2017 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28797635
6.
Enhanced reactive oxygen species through direct copper sulfide nanoparticle-doxorubicin complexation.
Nanotechnology
; 28(50): 505101, 2017 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29076808
7.
Transcriptional dynamics of bile salt export pump during pregnancy: mechanisms and implications in intrahepatic cholestasis of pregnancy.
Hepatology
; 60(6): 1993-2007, 2014 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24729004
8.
Bile salt export pump is dysregulated with altered farnesoid X receptor isoform expression in patients with hepatocellular carcinoma.
Hepatology
; 57(4): 1530-41, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23213087
9.
Mechanistic insights into isoform-dependent and species-specific regulation of bile salt export pump by farnesoid X receptor.
J Lipid Res
; 54(11): 3030-44, 2013 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-24002920
10.
Metabolism Pathways of Major Therapeutics for Treating Monkeypox Mono- and Co-infection with Human Immunodeficient Virus or SARS-CoV-2.
Curr Drug Metab
; 24(4): 240-249, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37287302
11.
Viral target and metabolism-based rationale for combined use of recently authorized small molecule COVID-19 medicines: Molnupiravir, nirmatrelvir, and remdesivir.
Fundam Clin Pharmacol
; 37(4): 726-738, 2023 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-36931725
12.
Oral Drug Delivery via Intestinal Lymphatic Transport Utilizing Lipid-Based Lyotropic Liquid Crystals.
Liquids (Basel)
; 3(4): 456-468, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-38711572
13.
Hypolipidemic agent Z-guggulsterone: metabolism interplays with induction of carboxylesterase and bile salt export pump.
J Lipid Res
; 53(3): 529-539, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22246918
14.
Covalent inhibition of carboxylesterase-2 by sofosbuvir and its effect on the hydrolytic activation of tenofovir disoproxil.
J Hepatol
; 66(3): 660-661, 2017 03.
Artigo
Inglês
| MEDLINE | ID: mdl-27965153
15.
Hollow copper sulfide nanoparticle-mediated transdermal drug delivery.
Small
; 8(20): 3143-50, 2012 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-22829400
16.
Surge in expression of carboxylesterase 1 during the post-neonatal stage enables a rapid gain of the capacity to activate the anti-influenza prodrug oseltamivir.
J Infect Dis
; 203(7): 937-42, 2011 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21402544
17.
Effect of alcohol exposure on the efficacy and safety of tenofovir alafenamide fumarate, a major medicine against human immunodeficiency virus.
Biochem Pharmacol
; 204: 115224, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36007574
18.
Breast Cancer MCF-7 Cell Spheroid Culture for Drug Discovery and Development.
J Cancer Ther
; 13(3): 117-130, 2022 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-36311820
19.
Covalent CES2 Inhibitors Protect against Reduced Formation of Intestinal Organoids by the Anticancer Drug Irinotecan.
Curr Drug Metab
; 2022 Dec 12.
Artigo
Inglês
| MEDLINE | ID: mdl-36515038
20.
Differentiated embryonic chondrocyte expressed gene-1 (DEC1) enhances the development of colorectal cancer with an involvement of the STAT3 signaling.
Neoplasia
; 27: 100783, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35334277